This 3rd edition has been updated to reflect current biosafety and biocontainment principles and practices. The document has been written with a performance-based approach, which not only accommodates contemporary state-of-the-art technologies and ever-changing approaches to achieving containment but provides simple and sensible solutions as well. Additions include sections on nonhuman primates, biomedical facilities using sheep as research animals, arthropods, and toxins. A separate section dedicated specifically to work with mycobacteria has also been included to reflect an ongoing area of concern to biosafety professionals and to outline a stratified approach to containment according to the type of procedures used.


Contents:

-Introduction
-Biological Safety
-Handling Infectious Substances
-Laboratory Design and Physical Requirements
-Commissioning, Certification and Recertification for CL3 and CL4 Laboratories
-Large Scale Production of Microorganisms
-Program Specific Guidelines
-Decontamination
-Biological Safety Cabinets
-Regulatory Aspects for Handling Infectious Substances