Biosafety in Microbiological and Biomedical Laboratories

U.S. Department of Health and Human Services | 01/12/2009
Tipología Arquitectura Estructura Laboratorios (p) Servicios Hospitalarios Servicios Centrales Diagnóstico y Tratamiento Documentación Documentos Biosafety in Microbiological and Biomedical Laboratories

Biosafety in Microbiological and Biomedical Laboratories (BMBL) quickly became the cornerstone of biosafety practice and policy in the United States upon first publication in 1984. Historically, the information in this publication has been advisory is nature even though legislation and regulation, in some circumstances, have overtaken it and made compliance with the guidance provided mandatory. We wish to emphasize that the 5th edition of the BMBL remains an advisory document recommending best practices for the safe conduct of work in biomedical and clinical laboratories from a biosafety perspective, and is not intended as a regulatory document though we recognize that it will be used that way by some.
Section I—Introduction
Section II—Biological Risk Assessment
Section III—Principles of Biosafety
Section IV—Laboratory Biosafety Level Criteria
Section V—Vertebrate Animal Biosafety Level Criteria for Vivarium Research Facilities
Section VI—Principles of Laboratory Biosecurity
Section VII—Occupational Health and Immunoprophylaxis
Section VIII—Agent Summary Statements
Appendix A – Primary Containment for Biohazards: Selection, Installation and Use of Biological Safety Cabinets
Appendix B—Decontamination and Disinfection
Appendix C—Transportation of Infectious Substances
Appendix D—Agriculture Pathogen Biosafety
Appendix E—Arthropod Containment Guidelines (ACG)
Appendix F—Select Agents and Toxins.
Appendix G—Integrated Pest Management (IPM)
Appendix H—Working with Human, NHP and Other Mammalian Cells and Tissues
Appendix I—Guidelines for Work with Toxins of Biological Origin
Appendix J—NIH Oversight of Research Involving Recombinant Biosafety Issues
Appendix K—Resources
Appendix L—Acronyms
Index


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